
Upneeq® Eyelid Lift

A non-invasive treatment for low-lying eyelids
Low-lying eyelids can make the eyes look tired, narrowed, or uneven — and for many patients, they can even interfere with daily activities such as reading, driving, or computer work. At Crestline Health and Wellness, we offer Upneeq®, the first and only FDA-approved prescription eyedrop for acquired ptosis (low-lying eyelids that develop over time).
Upneeq fits seamlessly into our mission: safe, effective treatments that support both function and confidence.
What is Upneeq?
Upneeq (oxymetazoline hydrochloride ophthalmic solution 0.1%) is a once-daily prescription eyedrop that temporarily lifts the upper eyelid. It works by activating Müller’s muscle — a small muscle in the upper lid responsible for maintaining eyelid elevation.
Many patients notice a lift within 5–15 minutes, with a visible effect that lasts for around 6–8 hours.
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Who may benefit from Upneeq?
Upneeq is designed for adults with acquired ptosis, meaning the eyelid droop began later in life rather than being present from birth. It may be helpful if you’ve noticed:
- Tired or heavy-appearing eyes
- Eyelids that sit lower than they used to
- Vision that feels “shadowed” or partially blocked
- Eye fatigue while reading or using screens
- A desire for a subtle, nonsurgical eyelid lift
Dr. Amy will evaluate whether Upneeq is appropriate for your needs and discuss any medical conditions or medications that should be considered first.
How does Upneeq work?
Upneeq gently stimulates the muscle that helps raise the upper eyelid.
This makes it different from cosmetic injectables or surgical procedures — it’s a non-invasive, drop-based treatment that offers temporary improvement without downtime.
Most patients apply one drop per eye in the morning and experience a natural-looking lift shortly after.


What to expect
- Quick appointment: The evaluation and prescription process is simple.
- Fast results: Visible lifting effect is often noticeable within minutes.
- Non-invasive: No needles, no surgery, no downtime.
- Easy to use: A single drop once per day.
- Natural look: Enhances the eyes without changing your overall appearance.
We take time with every patient to ensure they understand how to use the medication and what results to expect.
Safety and considerations
Upneeq is generally well tolerated. The most common side effects are mild and may include temporary irritation, dryness, or headache.
It may not be recommended for individuals with certain cardiovascular conditions or those taking medications that affect blood pressure. We will review your health history to make sure Upneeq is safe for you.


Why we offer Upneeq at Crestline Health and Wellness
Upneeq aligns with our clinic’s philosophy: thoughtful, evidence-based treatments that enhance quality of life. For patients bothered by low-lying eyelids — whether for functional or cosmetic reasons — Upneeq provides a meaningful, non-surgical option with very low risk and a fast onset of benefits.
Our goal is always the same: to support you in looking and feeling your best, with care that is personal, attentive, and grounded in patient-centered values.
We’re here to help. MAKE AN APPOINTMENT

COMPASSIONATE CARE
Located in the heart of Mountain Brook, we serve individuals throughout Central Alabama seeking relief from depression, anxiety, chronic pain, weight concerns, burnout, and more. Our clinic blends medical expertise with deeply personalized, patient-first care to help you feel better, function better, and live better.
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